مقایسه اثرات درمانی تتراسیکلین ،کوتریموکسازول و سیپروفلوکساسین در درمان بیماری وبا دربیمارستان فیروز آبادی

 ABSTRACT To evaluate the efficacy of Ciprofloxacin, Co-trimoxazole and Tetracyclin in the treatment of Cholerae a retrospective study was performed in Firooz - Abadi hospital in summer 1998. There were 173 patients , 71 patients received Tetracycline or Doxycyclin , 52 received Ciprofloxacin and the remaining 19 paitients received Co-trimoxazole. 14 patients were excluded from the study because they had recieved other antibiotics previously. There were also 16 patients who did not receive any antibiotics,and were considered as control group.To compare the therapeatic effect of anibiotics these factors are considered: 1) Having a positive stool culture(s/c) before admission. 2) The severity of disease. 3) Time of response to treatment. 4) Duration of treatmet. We compared “ time of response to treatment” in each two groups and calculated P value and found out that neither of the P-values were meaningfull that means non of the antibiotics had more efficacy than the others to decrease the time of treatment. In another evaluation we compared each two groups for the “ Duration of treatment ”and Calculated P-value and there was no statistically meaningfull values. This means non of antibiotics is more efficient than the others to decreas “ mean duration of treatment”. In conclusion, all the antibiotics used for the treatment of cholerae in Firooz–Abadi hospital in summer 1998 were effective to decrease time of treatment and there was no difference in the therapeatic groups.